Antibody

β-Amyloid

Tools

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Clonality: polyclonal
Host: Rabbit
Source: Cell Signaling
Cat# 2454
Reference:
Zempel H, 2010
Formulation: liquid, HEPES, NaCl, BSA, glycerol, affinity purified
Reactivity:
Reacts in: Bovine, Human, Rat

Immunogen/Epitope

immunogen = synthetic peptide corresp. to residues at the N-terminus of human β-Amyloid peptides

Specificity

detects several isoforms of β-amyloid peptide (Abeta), such as Abeta-40, Abeta-42 etc, regardless of phosphorylation state

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References

Paper Citations

  1. . Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines. J Neurosci. 2010 Sep 8;30(36):11938-50. PubMed.

Further Reading

No Available Further Reading