Kester MI, Goos JD, Teunissen CE, Benedictus MR, Bouwman FH, Wattjes MP, Barkhof F, Scheltens P, van der Flier WM. Associations between cerebral small-vessel disease and Alzheimer disease pathology as measured by cerebrospinal fluid biomarkers. JAMA Neurol. 2014 Jul 1;71(7):855-62. PubMed.
AlzBiomarker Database
Meta-Analysis
Curated Study Data
| Biomarker (Source) |
Cohort (N) |
Measurement Mean ± SD |
Method; Assay Name; Manufacturer |
Diagnostic Criteria |
|---|---|---|---|---|
| Aβ42 (CSF) |
AD (547) |
490 ± 176 pg/mL |
ELISA; Innotest; Innogenetics |
McKhann et al., 1984 |
| Aβ42 (CSF) |
VaD (30) |
638 ± 233 pg/mL |
ELISA; Innotest; Innogenetics |
Román et al., 1993 |
| tau-p181 (CSF) |
AD (547) |
89 ± 40 pg/mL |
ELISA; Innotest; Innogenetics |
McKhann et al., 1984 |
| tau-p181 (CSF) |
VaD (30) |
42 ± 19 pg/mL |
ELISA; Innotest; Innogenetics |
Román et al., 1993 |
| tau-total (CSF) |
AD (547) |
692 ± 404 pg/mL |
ELISA; Innotest; Innogenetics |
McKhann et al., 1984 |
| tau-total (CSF) |
VaD (30) |
312 ± 180 pg/mL |
ELISA; Innotest; Innogenetics |
Román et al., 1993 |
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