PAPER Wu J, He Y, Liang S, Liu Z, Huang J, Liu W, Tao J, Chen L, Chan CC, Lee TM
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PAPER Lou K, Liu S, Zhang F, Sun W, Su X, Bi W, Yin Q, Qiu Y, Zhang Z, Jing M, Ma S
The effect of hyperthyroidism on cognitive function, neuroinflammation, and necroptosis in APP/PS1 mice.
J Transl Med. 2023 Sep 22;21(1):657. PubMed.PAPER Basu S, Song M, Adams L, Jeong I, Je G, Guhathakurta S, Jiang J, Boparai N, Dai W, Cardozo-Pelaez F, Tatulian SA, Han KY, Elliott J, Baum J, McLean PJ, Dickson DW, Kim YS
Transcriptional mutagenesis of α-synuclein caused by DNA oxidation in Parkinson's disease pathogenesis.
Acta Neuropathol. 2023 Nov;146(5):685-705. Epub 2023 Sep 23 PubMed.PAPER Mundada NS, Rojas JC, Vandevrede L, Thijssen EH, Iaccarino L, Okoye OC, Shankar R, Soleimani-Meigooni DN, Lago AL, Miller BL, Teunissen CE, Heuer H, Rosen HJ, Dage JL, Jagust WJ, Rabinovici GD, Boxer AL, La Joie R
Head-to-head comparison between plasma p-tau217 and flortaucipir-PET in amyloid-positive patients with cognitive impairment.
Alzheimers Res Ther. 2023 Sep 22;15(1):157. PubMed.PAPER Emmerson JT, Do Carmo S, Liu Y, Shalhoub A, Liu A, Bonomo Q, Malcolm JC, Breuillaud L, Martinez-Trujillo JC, Cuello AC
Corrigendum to "Progressive human-like tauopathy with downstream neurodegeneration and neurovascular compromise in a transgenic rat model" [Neurobiol of Disease 184 (2023),106227 / YNBDI_106227].
Neurobiol Dis. 2023 Oct 15;187:106301. Epub 2023 Sep 22 PubMed.PAPER Blackman J, Morrison HD, Gabb V, Biswas B, Li H, Turner N, Jolly A, Trender W, Hampshire A, Whone A, Coulthard E
Remote evaluation of sleep to enhance understanding of early dementia due to Alzheimer's Disease (RESTED-AD): an observational cohort study protocol.
BMC Geriatr. 2023 Sep 23;23(1):590. PubMed.PAPER Ducharme S, Pijnenburg Y, Rohrer JD, Huey E, Finger E, Tatton N
Identifying and Diagnosing TDP-43 Neurodegenerative Diseases in Psychiatry.
Am J Geriatr Psychiatry. 2024 Jan;32(1):98-113. Epub 2023 Sep 3 PubMed.PAPER Chakraborty P, Rivière G, Hebestreit A, de Opakua AI, Vorberg IM, Andreas LB, Zweckstetter M
Acetylation discriminates disease-specific tau deposition.
Nat Commun. 2023 Sep 22;14(1):5919. PubMed.PAPER Kas A, Rozenblum L, Pyatigorskaya N
Clinical Value of Hybrid PET/MR Imaging: Brain Imaging Using PET/MR Imaging.
Magn Reson Imaging Clin N Am. 2023 Nov;31(4):591-604. Epub 2023 Aug 8 PubMed.PAPER Wang X, Deng H, Lin J, Zhang K, Ni J, Li L, Fan G
Distinct roles of telomerase activity in age-related chronic diseases: An update literature review.
Biomed Pharmacother. 2023 Nov;167:115553. Epub 2023 Sep 20 PubMed.PAPER de Fàbregues O, Sellés M, Ramos-Vicente D, Roch G, Vila M, Bové J
Relevance of tissue-resident memory CD8 T cells in the onset of Parkinson's disease and examination of its possible etiologies: infectious or autoimmune?
Neurobiol Dis. 2023 Oct 15;187:106308. Epub 2023 Sep 21 PubMed.PAPER
Corrigendum to "Generation of a set of isogenic, gene-edited iPSC lines homozygous for all main APOE variants and an APOE knock-out line" [Stem Cell Res. 34/1873-5061 (2019) 101349-55].
.Heinz Hillen on Donanemab Data Anchors Upbeat AAIC
COMMENT These data are a big step forward toward effective treatment and prevention in AD. Together with results from previous clinically effective and ineffective amyloid-modulating antibodies and low molecular-weight compounds, we should now be positioned to ad
Oskar Hansson on Donanemab Data Anchors Upbeat AAIC
COMMENT It is remarkable that we now have several anti-amyloid therapies that have been proven to slow down the disease progression of Alzheimer’s disease when initiated in amyloid-positive patients with amnestic MCI or mild dementia. While the donanemab Phase 2
Give BACE Inhibitors a Second Chance?
CONFERENCE COVERAGE 2023-07-29 Conference Coverage Scientists once hoped that blocking β-secretase would slow or prevent Alzheimer’s disease. Then came the rude awakening. The inhibitors caused the very thing they were supposed to prevent—cognitive decline. Enthusiasm tanked. Pharmaceu
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