Antibody
p38 MAPK phos Thr180/Tyr182 (3D7)
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Clonality: monoclonal
Host: Rabbit
Isotype: IgG
Source: Cell Signaling
Cat# 9215
Reference:
Bosco DA, 2010
Formulation: liquid, HEPES, NaCl, BSA, glycerol
Reactivity:
Reacts in: Mink, Human, Monkey, Mouse, Rat
Immunogen/Epitope
Immunogen = synthetic phospho-peptide corresp. to residues surrounding Thr180/Tyr182 of human p38 MAP kinase conj. to KLH
Specificity
Detects endogenous levels of p38 MAP kinase only when dually phosphorylated at Thr180 and Tyr182. Does not cross-react with the phosphorylated forms of either p42/44 MAPK or SAPK/JNK
References
Paper Citations
- Bosco DA, Morfini G, Karabacak NM, Song Y, Gros-Louis F, Pasinelli P, Goolsby H, Fontaine BA, Lemay N, McKenna-Yasek D, Frosch MP, Agar JN, Julien JP, Brady ST, Brown RH. Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS. Nat Neurosci. 2010 Nov;13(11):1396-403. PubMed.
Further Reading
No Available Further Reading
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