Antibody
PrP (12B2)
Quick Links
Clonality: monoclonal
Host: Mouse
Source: Reference:
Dossena, 2008
(provided by Jan PM Langeveld, CIDC-Lelystad, the Netherlands)
Reactivity:
Reacts in: Bovine, Ovine
Reference: <br /><a href="http://www.biomedcentral.com/content/pdf/1746-6148-2-19.pdf" target="_new">Langeveld, et al., 2006</a>
Immunogen/Epitope
immunogen = bovine PrP aa 97-115, corresp to ovine PrP sequence 89–107, conj to KLH at C-terminus. (epitope at 93WGQGG97)
Specificity
recognizes PrP, PK-cleavage site specific
References
Paper Citations
- Dossena S, Imeri L, Mangieri M, Garofoli A, Ferrari L, Senatore A, Restelli E, Balducci C, Fiordaliso F, Salio M, Bianchi S, Fioriti L, Morbin M, Pincherle A, Marcon G, Villani F, Carli M, Tagliavini F, Forloni G, Chiesa R. Mutant prion protein expression causes motor and memory deficits and abnormal sleep patterns in a transgenic mouse model. Neuron. 2008 Nov 26;60(4):598-609. PubMed.
External Citations
Further Reading
No Available Further Reading
Comments / Questions
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