Roher AE, Esh CL, Kokjohn TA, Castaño EM, Van Vickle GD, Kalback WM, Patton RL, Luehrs DC, Daugs ID, Kuo YM, Emmerling MR, Soares H, Quinn JF, Kaye J, Connor DJ, Silverberg NB, Adler CH, Seward JD, Beach TG, Sabbagh MN. Amyloid beta peptides in human plasma and tissues and their significance for Alzheimer's disease. Alzheimers Dement. 2009 Jan;5(1):18-29. PubMed.
AlzBiomarker Database
Meta-Analysis
- AD vs CTRL : Aβ40 (Plasma and Serum)
- CTRL vs AD : Aβ40 (Plasma and Serum)
- AD vs CTRL : Aβ42 (Plasma and Serum)
- CTRL vs AD : Aβ42 (Plasma and Serum)
Curated Study Data
| Biomarker (Source) |
Cohort (N) |
Measurement Mean ± SD |
Method; Assay Name; Manufacturer |
Diagnostic Criteria |
|---|---|---|---|---|
| Aβ40 (Plasma) |
AD (17) |
424.06 ± 147.73 pg/mL |
ELISA; Other/Not Specified; Immuno-Biological Laboratories |
McKhann et al., 1984 |
| Aβ40 (Plasma) |
CTRL- CNC (21) |
344.41 ± 132.43 pg/mL |
ELISA; Other/Not Specified; Immuno-Biological Laboratories |
|
| Aβ42 (Plasma) |
AD (17) |
149.91 ± 77.82 pg/mL |
ELISA; Innotest; Innogenetics |
McKhann et al., 1984 |
| Aβ42 (Plasma) |
CTRL- CNC (21) |
124.71 ± 42.34 pg/mL |
ELISA; Innotest; Innogenetics |
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