de Leeuw SM, Kirschner AW, Lindner K, Rust R, Budny V, Wolski WE, Gavin AC, Nitsch RM, Tackenberg C. APOE2, E3, and E4 differentially modulate cellular homeostasis, cholesterol metabolism, and inflammatory response in isogenic iPSC-derived astrocytes. Stem Cell Reports. 2022 Jan 11;17(1):110-126. Epub 2021 Dec 16 PubMed.

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Mutations

  1. APOE C130R (ApoE4)