Venkataramani V, Thiele K, Behnes CL, Wulf GG, Thelen P, Opitz L, Salinas-Riester G, Wirths O, Bayer TA, Schweyer S. Amyloid precursor protein is a biomarker for transformed human pluripotent stem cells. Am J Pathol. 2012 Apr;180(4):1636-52. Epub 2012 Feb 1 PubMed.

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- Roberta Diaz Brinton
  College of Medicine, University of Arizona
- Posted: 14 Feb 2012
In addition to the novel and important findings that APP expression co-varies with stem cell markers, and that its expression can be epigenetically regulated, Venkataramani and colleagues describe their novel strategy for discerning a potential function of APP in human pluripotent stem cells.

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- Craig Atwood
  University of Wisconsin
- Posted: 21 Feb 2012
Venkataramani and colleagues add to the growing literature regarding the role of APP in mediating stem cell fate as recently reported by Porayette et al., 2009, and Freude et al., 2011.

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