Yang CC, Chiu MJ, Chen TF, Chang HL, Liu BH, Yang SY. Assay of Plasma Phosphorylated Tau Protein (Threonine 181) and Total Tau Protein in Early-Stage Alzheimer's Disease. J Alzheimers Dis. 2018;61(4):1323-1332. PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)		 Cohort
(N)		 Measurement
Mean ± SD		 Method;
Assay Name;
Manufacturer		 Diagnostic
Criteria
tau-p181
(Plasma)		 AD
(21)		 6.14 ± 1.59
pg/mL		 Immunomagnetic Reduction;
Other/Not Specified;
In-house		 McKhann et al., 2011
tau-p181
(Plasma)		 CTRL-
CNC
(23)		 2.46 ± 1.09
pg/mL		 Immunomagnetic Reduction;
Other/Not Specified;
In-house
tau-total
(Plasma)		 AD
(21)		 37.54 ± 12.29
pg/mL		 Immunomagnetic Reduction;
MF-TAU-0060;
MagQu Co. Ltd.		 McKhann et al., 2011
tau-total
(Plasma)		 CTRL-
CNC
(23)		 18.85 ± 10.16
pg/mL		 Immunomagnetic Reduction;
MF-TAU-0060;
MagQu Co. Ltd.

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