Hatzipetros T, Bogdanik LP, Tassinari VR, Kidd JD, Moreno AJ, Davis C, Osborne M, Austin A, Vieira FG, Lutz C, Perrin S. C57BL/6J congenic Prp-TDP43A315T mice develop progressive neurodegeneration in the myenteric plexus of the colon without exhibiting key features of ALS. Brain Res. 2014 Oct 10;1584:59-72. Epub 2013 Oct 18 PubMed.

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News

  1. Paper Alert: TDP-43 Mouse No Model to Test ALS Therapeutics

Research Models

  1. TARDBP (A315T) (congenic)
  2. TARDBP (A315T) (hybrid)