Le Ber I, De Septenville A, Guerreiro R, Bras J, Camuzat A, Caroppo P, Lattante S, Couarch P, Kabashi E, Bouya-Ahmed K, Dubois B, Brice A. Homozygous TREM2 mutation in a family with atypical frontotemporal dementia. Neurobiol Aging. 2014 Oct;35(10):2419.e23-2419.e25. Epub 2014 Apr 18 PubMed.

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Mutations

  1. TREM2 T66M

Research Models

  1. Trem2 T66M KI
  2. Trem2 KO (JAX)
  3. Trem2 KO (KOMP)
  4. Trem2 KO (KOMP) x htau
  5. Trem2 KO (Colonna)
  6. Trem2 KO (Colonna) x 5XFAD
  7. Trem2 KO (Colonna) x PS19