Cloe AL, Orgel JP, Sachleben JR, Tycko R, Meredith SC. The Japanese mutant Aβ (ΔE22-Aβ(1-39)) forms fibrils instantaneously, with low-thioflavin T fluorescence: seeding of wild-type Aβ(1-40) into atypical fibrils by ΔE22-Aβ(1-39). Biochemistry. 2011 Mar 29;50(12):2026-39. Epub 2011 Feb 24 PubMed.

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Mutations

  1. APP E693del (Osaka)