Leverenz JB, Fishel MA, Peskind ER, Montine TJ, Nochlin D, Steinbart E, Raskind MA, Schellenberg GD, Bird TD, Tsuang D. Lewy body pathology in familial Alzheimer disease: evidence for disease- and mutation-specific pathologic phenotype. Arch Neurol. 2006 Mar;63(3):370-6. PubMed.
Recommends
Please login to recommend the paper.
Comments
RIKEN Center for Brain Science
This work is interesting in describing the difference in pathological phenptypes between PS1 and PS2 carriers. The Lewy body pathology could be a gain-of-function phenotype of PS mutations. The paper would have been more significant if the authors also included data from sporadic AD.
Make a Comment
To make a comment you must login or register.