Paper
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Zheng B, Liao Z, Locascio JJ, Lesniak KA, Roderick SS, Watt ML, Eklund AC, Zhang-James Y, Kim PD, Hauser MA, Grünblatt E, Moran LB, Mandel SA, Riederer P, Miller RM, Federoff HJ, Wüllner U, Papapetropoulos S, Youdim MB, Cantuti-Castelvetri I, Young AB, Vance JM, Davis RL, Hedreen JC, Adler CH, Beach TG, Graeber MB, Middleton FA, Rochet JC, Scherzer CR, . PGC-1α, a potential therapeutic target for early intervention in Parkinson's disease. Sci Transl Med. 2010 Oct 6;2(52):52ra73. PubMed.
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Comments
Johns Hopkins University School of Medicine
I strongly recommend the paper. It’s really interesting to know that PGC-1α slows down the progression of the disease. The authors have focused on an important aspect which might be an appealing target for drugs and also help to detect PD symptoms at an early stage.
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