Zhao X, Lin Y, Liou B, Fu W, Jian J, Fannie V, Zhang W, Setchell KD, Grabowski GA, Sun Y, Liu CJ. PGRN deficiency exacerbates, whereas a brain penetrant PGRN derivative protects, GBA1 mutation-associated pathologies and diseases. Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2210442120. Epub 2022 Dec 27 PubMed.

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Research Models

  1. Gba1 D409V KI Mouse (Grabowski)