. The Phospholipase Cγ2 Mutants R665W and L845F Identified in Ibrutinib-resistant Chronic Lymphocytic Leukemia Patients Are Hypersensitive to the Rho GTPase Rac2 Protein. J Biol Chem. 2016 Oct 14;291(42):22136-22148. Epub 2016 Aug 19 PubMed.

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Research Models

  1. Plcg2*M28L x 5xFAD
  2. Plcg2*P522R x 5xFAD