Katsarou M, Stratikos E, Chroni A. Thermodynamic destabilization and aggregation propensity as the mechanism behind the association of apoE3 mutants and lipoprotein glomerulopathy. J Lipid Res. 2018 Dec;59(12):2339-2348. Epub 2018 Oct 11 PubMed.

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Mutations

  1. APOE R43C (Kyoto)
  2. APOE R132C (Tsukuba)
  3. APOE A170D