Therapeutics
MKC-231
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Overview
Name: MKC-231
Therapy Type: Small Molecule (timeline)
Target Type: Unknown
Condition(s): Alzheimer's Disease
U.S. FDA Status: Alzheimer's Disease (Inactive)
Company: Mitsubishi Tanabe Pharma
Approved for: None
Background
MKC-231 is reported to enhance high-affinity choline uptake (HACU), a rate-limiting step in acetylcholine synthesis (Takashina et al., 2008).
Last Updated: 09 Jan 2014
References
Paper Citations
- Takashina K, Bessho T, Mori R, Kawai K, Eguchi J, Saito K. MKC-231, a choline uptake enhancer: (3) Mode of action of MKC-231 in the enhancement of high-affinity choline uptake. J Neural Transm. 2008 Jul;115(7):1037-46. Epub 2008 May 7 PubMed.
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