Alzpedia
SORLA (SORL1)
Synonyms: Sorting protein-related receptor containing LDLR class-A repeats, Sortilin-related receptor, SORLA1, LR11, LRP9, gp250, C11orf32
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References
Alzpedia Citations
Further Reading
News
- Coming Into Vogue? Retromer in APP Processing, AD Pathogenesis
- Traffic Control: BDNF Boosts SORLA, Reroutes APP
- Aβ and SORLA—Partners in Cerebrovascular Crime?
- Sorting Out SorLA—What Role in APP Processing, AD?
- SORLA Soars—Large Study Links Gene to Late-onset AD
- Sorrento: Sorting Out Shedding of Ectodomains
- Sorting Out SORL1: 500+ Mutations Mapped, Prioritized in Alzforum Dataset
- Hundreds of SORL1 Variants Mapped in Alzforum Database; SORL1 Cast as Causal AD Gene
Papers
- Willnow TE, Andersen OM. Sorting receptor SORLA - a trafficking path to avoid Alzheimer disease. J Cell Sci. 2013 Jul 1;126(Pt 13):2751-60. PubMed.
- Fjorback AW, Andersen OM. SorLA is a molecular link for retromer-dependent sorting of the Amyloid precursor protein. Commun Integr Biol. 2012 Nov 1;5(6):616-9. PubMed.
- Jin C, Liu X, Zhang F, Wu Y, Yuan J, Zhu J, Wang G, Cheng Z. An Updated Meta-Analysis of the Association between SORL1 Variants and the Risk for Sporadic Alzheimer's Disease. J Alzheimers Dis. 2013;37(2):429-37. PubMed.
- Pallesen LT, Vægter CB. Sortilin and SorLA regulate neuronal sorting of trophic and dementia-linked proteins. Mol Neurobiol. 2012 Apr;45(2):379-87. PubMed.
- Wagner T, Pietrzik CU. The role of lipoprotein receptors on the physiological function of APP. Exp Brain Res. 2011 Sep 23; PubMed.
- Hermey G. The Vps10p-domain receptor family. Cell Mol Life Sci. 2009 Aug;66(16):2677-89. PubMed.