Zhang J, Sokal I, Peskind ER, Quinn JF, Jankovic J, Kenney C, Chung KA, Millard SP, Nutt JG, Montine TJ. CSF multianalyte profile distinguishes Alzheimer and Parkinson diseases. Am J Clin Pathol. 2008 Apr;129(4):526-9. PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)		 Cohort
(N)		 Measurement
Mean ± SD		 Method;
Assay Name;
Manufacturer		 Diagnostic
Criteria
Aβ42
(CSF)		 AD
(48)		 268.5 ± 27.1†
pg/mL		 xMAP;
Other/Not Specified;
Invitrogen		 McKhann et al., 1984
Aβ42
(CSF)		 CTRL-
CNC
(95)		 371.8 ± 20.5†
pg/mL		 xMAP;
Other/Not Specified;
Invitrogen
Aβ42
(CSF)		 PD
(40)		 510.6 ± 27.8†
pg/mL		 xMAP;
Other/Not Specified;
Invitrogen		 Gelb et al., 1999
tau-total
(CSF)		 AD
(48)		 1425 ± 104.3†
pg/mL		 xMAP;
Other/Not Specified;
Invitrogen		 McKhann et al., 1984
tau-total
(CSF)		 CTRL-
CNC
(95)		 690.2 ± 39.1†
pg/mL		 xMAP;
Other/Not Specified;
Invitrogen
tau-total
(CSF)		 PD
(40)		 387.8 ± 46.9†
pg/mL		 xMAP;
Other/Not Specified;
Invitrogen		 Gelb et al., 1999

† Mean ± SEM

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AlzBiomarker

  1. AD vs CTRL : Aβ42 (CSF)
  2. CTRL vs AD : Aβ42 (CSF)
  3. PD vs AD : Aβ42 (CSF)
  4. AD vs CTRL : tau-total (CSF)
  5. CTRL vs AD : tau-total (CSF)
  6. PD vs AD : tau-total (CSF)