Jobs
Postdoctoral Fellow
Posted 29 May 2025
Employer
University College London
Location
London, England, United Kingdom
Principal Investigator
Contact
Informal enquiries regarding the role can be addressed to Dr Marc Aurel Busche (m.busche@ucl.ac.uk).
Description
This is an opportunity to work independently on a high-impact, state-of-the-art project in a cutting-edge research laboratory at the U.K. Dementia Research Institute at UCL. It is seeking an exceptional individual to lead a innovative research program aimed at understanding—and ultimately reversing—neuronal and circuit dysfunction in Alzheimer’s disease. The focus will be on linking early, cell-type-specific molecular alterations to large-scaleneural circuit impairments in mouse models, and on testing gene-therapeutic approaches to restore normal function.
The project will utilize advanced techniques such as in vivo two-photon calcium imaging and/or Neuropixels electrophysiology to record neuronal activity across large populations of cells. A variety of experimental and analytical approaches will be applied to interrogate the mechanisms of dysfunction and evaluate novel therapeutic interventions.
The post is available from 01 July 2025 and funded by the UK DRI until 30 April 2027 in the first instance.
For more information and to apply, please see:
Requirements
A Ph.D. in neuroscience, engineering, computer science, mathematics, physics, or a related field, and have practical experience with in vivo two-photon calcium imaging and/or Neuropixels electrophysiology.
A strong background in analytical and/or statistical analysis, along with proficient programming and coding skills, is essential for the role. Excellent interpersonal, collaboration, and communication skills are also required.
This role meets the eligibility requirements for a skilled worker certificate of sponsorship or a global talent visa under U.K. visas and Immigration legislation. Therefore, UCL welcomes applications from international applicants who require a visa.