Murphy KB, Hu D, Wolfs L, Rohde SK, Fauró GL, Geric I, Mancuso R, De Strooper B, Marzi SJ. The APOE isoforms differentially shape the transcriptomic and epigenomic landscapes of human microglia xenografted into a mouse model of Alzheimer's disease. Nat Commun. 2025 May 27;16(1):4883. PubMed.

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Mutations

  1. APOE C130R (ApoE4)