Lee JH, Cheng R, Schupf N, Manly J, Lantigua R, Stern Y, Rogaeva E, Wakutani Y, Farrer L, St George-Hyslop P, Mayeux R. The association between genetic variants in SORL1 and Alzheimer disease in an urban, multiethnic, community-based cohort. Arch Neurol. 2007 Apr;64(4):501-6. PubMed.

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News

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  3. Gaining Notoriety, SORL1 Claims Spot Among Top Alzheimer’s Genes

Mutations

  1. SORL1 H269H (SNP 7)
  2. SORL1 A528T (SNP 13)
  3. SORL1 T833T (SNP 16)
  4. SORL1 S1187S (SNP 19)
  5. SORL1 N1246N (SNP 22)
  6. SORL1 A1584A (SNP 23)

Research Timeline Event

  1. Sorl1 variants increase risk of LOAD