. Cerebrospinal fluid soluble TREM2 in aging and Alzheimer's disease. Alzheimers Res Ther. 2016 Apr 27;8(1):17. PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)
Cohort
(N)
Measurement
Mean ± SD
Method;
Assay Name;
Manufacturer
Diagnostic
Criteria
sTREM2
(CSF)
AD
(25)
4.2 ± 1.9
ng/mL §
ELISA;
In-house;
In-house
McKhann et al., 1984
sTREM2
(CSF)
AD
(29)
5.5 ± 3
ng/mL §
ELISA;
In-house;
In-house
McKhann et al., 1984
sTREM2
(CSF)
CTRL-
Other Controls
(25)
3.9 ± 1.7
ng/mL §
ELISA;
In-house;
In-house
sTREM2
(CSF)
CTRL-
Other Controls
(50)
4.7 ± 2.2
ng/mL §
ELISA;
In-house;
In-house

§ Data supplied to Alzforum by author

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This paper appears in the following:

Mutations

  1. TREM2 T66M

Research Models

  1. Trem2 T66M KI

AlzBiomarker

  1. AD vs CTRL : sTREM2 (CSF)
  2. CTRL vs AD : sTREM2 (CSF)