Jung NY, Kim ES, Kim HS, Jeon S, Lee MJ, Pak K, Lee JH, Lee YM, Lee K, Shin JH, Ko JK, Lee JM, Yoon JA, Hwang C, Choi KU, Lee EC, Seong JK, Huh GY, Kim DS, Kim EJ. Comparison of Diagnostic Performances Between Cerebrospinal Fluid Biomarkers and Amyloid PET in a Clinical Setting. J Alzheimers Dis. 2020;74(2):473-490. PubMed.

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Curated Study Data

Biomarker (Source)	Cohort (N)	Measurement Mean ± SD	Method; Assay Name; Manufacturer	Diagnostic Criteria
Aβ42 (CSF)	AD (62)	511.6 ± 197.3 pg/mL §	ELISA; ; Fujirebio	McKhann et al., 2011
Aβ42 (CSF)	CTRL- CNC (27)	840.3 ± 196 pg/mL §	ELISA; ; Fujirebio
Aβ42 (CSF)	FTD- bvFTD, svPPA, nfvPPA, FTD with motor neuron disease (14)	809.6 ± 286.4 pg/mL §	ELISA; ; Fujirebio	Rascovsky et al., 2011; Gorno-Tempini et al., 2011
Aβ42 (CSF)	NPH (27)	678 ± 216.4 pg/mL §	ELISA; ; Fujirebio
tau-p181 (CSF)	AD (62)	80.5 ± 34.9 pg/mL §	ELISA; ; Fujirebio	McKhann et al., 2011
tau-p181 (CSF)	CTRL- CNC (27)	40.8 ± 11.7 pg/mL §	ELISA; ; Fujirebio
tau-p181 (CSF)	FTD- bvFTD, svPPA, nfvPPA, FTD with motor neuron disease (14)	50 ± 28.6 pg/mL §	ELISA; ; Fujirebio	Rascovsky et al., 2011; Gorno-Tempini et al., 2011
tau-p181 (CSF)	NPH (27)	34.2 ± 16.2 pg/mL §	ELISA; ; Fujirebio
tau-total (CSF)	AD (62)	537.9 ± 327.6 pg/mL §	ELISA; ; Fujirebio	McKhann et al., 2011
tau-total (CSF)	CTRL- CNC (27)	192.1 ± 72.6 pg/mL §	ELISA; ; Fujirebio
tau-total (CSF)	FTD- bvFTD, svPPA, nfvPPA, FTD with motor neuron disease (14)	307.9 ± 186 pg/mL §	ELISA; ; Fujirebio	Rascovsky et al., 2011; Gorno-Tempini et al., 2011
tau-total (CSF)	NPH (27)	178.5 ± 104.2 pg/mL §	ELISA; ; Fujirebio

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