Schmidt FM, Mergl R, Stach B, Jahn I, Gertz HJ, Schönknecht P. Elevated levels of cerebrospinal fluid neuron-specific enolase (NSE) in Alzheimer's disease. Neurosci Lett. 2014 Jun 6;570:81-5. Epub 2014 Apr 16 PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)		 Cohort
(N)		 Measurement
Mean ± SD		 Method;
Assay Name;
Manufacturer		 Diagnostic
Criteria
NSE
(CSF)		 AD
(32)		 20.45 ± 7.21
ng/mL		 Electrochemiluminescence;
Other/Not Specified;
Roche Diagnostics
NSE
(CSF)		 CTRL-
CNC
(32)		 6.43 ± 4.1
ng/mL		 Electrochemiluminescence;
Elecsys;
Roche Diagnostics
tau-p181
(CSF)		 AD
(32)		 79.19 ± 36.2
pg/mL		 ELISA;
Innotest;
Innogenetics
tau-p181
(CSF)		 CTRL-
CNC
(32)		 33.93 ± 13.79
pg/mL		 ELISA;
Innotest;
Innogenetics
tau-total
(CSF)		 AD
(32)		 470.53 ± 260.44
pg/mL		 ELISA;
Innotest;
Innogenetics
tau-total
(CSF)		 CTRL-
CNC
(32)		 137.1 ± 53.33
pg/mL		 ELISA;
Innotest;
Innogenetics

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This paper appears in the following:

AlzBiomarker

  1. AD vs CTRL : NSE (CSF)
  2. CTRL vs AD : NSE (CSF)
  3. AD vs CTRL : tau-p181 (CSF)
  4. CTRL vs AD : tau-p181 (CSF)
  5. AD vs CTRL : tau-total (CSF)
  6. CTRL vs AD : tau-total (CSF)