Therapeutics
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| Name | Synonyms | FDA Status | Company | Target Type | Therapy Type | Approved For |
|---|---|---|---|---|---|---|
| AAB-003 | PF-05236812 | Alzheimer's Disease (Discontinued) | Janssen, Pfizer | Amyloid-Related | Immunotherapy (passive) | |
| ABBV-916 | N3pG-Abeta mAb | Alzheimer's Disease (Discontinued) | AbbVie | Amyloid-Related | Immunotherapy (passive) | |
| AL002 | Alzheimer's Disease (Discontinued) | AbbVie, Alector | Inflammation | Immunotherapy (passive) | ||
| AL003 | Alzheimer's Disease (Discontinued) | AbbVie, Alector | Inflammation | Immunotherapy (passive) | ||
| Bapineuzumab | AAB-001 | Alzheimer's Disease (Discontinued) | Janssen, Pfizer | Amyloid-Related | Immunotherapy (passive) | |
| BIIB076 | NI-105, 6C5 huIgG1/l |
Alzheimer's Disease (Discontinued) | Biogen, Eisai Co., Ltd., Neurimmune | Tau | Immunotherapy (passive) | |
| Cinpanemab | BIIB054, NI-202 |
Parkinson's Disease (Discontinued) | Biogen, Neurimmune | alpha-synuclein | Immunotherapy (passive) | |
| Crenezumab | MABT5102A , RG7412 |
Alzheimer's Disease (Discontinued) | AC Immune SA, Genentech, Hoffmann-La Roche | Amyloid-Related | Immunotherapy (passive) | None |
| DNL919 | TAK-920, ATV:TREM2 |
Alzheimer's Disease (Discontinued) | Denali Therapeutics Inc., Takeda Pharmaceutical Company | Amyloid-Related, Inflammation | Immunotherapy (passive) | |
| Gammagard® | Intravenous Immunoglobulin, IVIg |
Alzheimer's Disease (Discontinued) | Baxter Healthcare | Amyloid-Related, Inflammation | Immunotherapy (passive) | Immunodeficiency conditions |
| Gantenerumab | RO4909832, RG1450, R1450 |
Alzheimer's Disease (Discontinued) | Chugai Pharmaceutical Co., Ltd., Hoffmann-La Roche | Amyloid-Related | Immunotherapy (passive) | |
| Gosuranemab | BIIB092, BMS-986168, IPN007 |
Progressive Supranuclear Palsy (Discontinued), Alzheimer's Disease (Discontinued) | Biogen, Bristol-Myers Squibb | Tau | Immunotherapy (passive) | |
| Latozinemab | AL001, GSK4527223 |
Frontotemporal Dementia (Discontinued), Amyotrophic Lateral Sclerosis (Inactive) | Alector, GlaxoSmithKline (GSK) | Other | Immunotherapy (passive) | |
| LY2599666 | Alzheimer's Disease (Discontinued) | Eli Lilly & Co. | Amyloid-Related | Immunotherapy (passive) | ||
| MEDI1814 | Alzheimer's Disease (Discontinued) | AstraZeneca, Eli Lilly & Co. | Amyloid-Related | Immunotherapy (passive) | ||
| Ponezumab | PF-04360365 | Alzheimer's Disease (Discontinued), Cerebral Amyloid Angiopathy (Discontinued) | Pfizer | Amyloid-Related | Immunotherapy (passive) | None |
| RG7345 | RO6926496 | Alzheimer's Disease (Discontinued) | Tau | Immunotherapy (passive) | ||
| SAR228810 | Alzheimer's Disease (Discontinued) | Sanofi | Amyloid-Related | Immunotherapy (passive) | ||
| Solanezumab | LY2062430 | Alzheimer's Disease (Discontinued) | Eli Lilly & Co. | Amyloid-Related | Immunotherapy (passive) | None |
| Tilavonemab | ABBV-8E12, C2N 8E12, HJ8.5 |
Progressive Supranuclear Palsy (Discontinued), Alzheimer's Disease (Discontinued) | AbbVie, C2N Diagnostics, LLC | Tau | Immunotherapy (passive) | |
| VGL101 | Iluzanebart | Adult-onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia (Discontinued) | Vigil Neuroscience, Inc. | Inflammation, Other | Immunotherapy (passive) | |
| Zagotenemab | LY3303560 | Alzheimer's Disease (Discontinued) | Eli Lilly & Co. | Tau, Unknown | Immunotherapy (passive) |