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Name Synonyms FDA Status Company Target Type Therapy Type Approved
For
ACI-3024 Tau MorphomerTM Alzheimer's Disease (Inactive), Other Tauopathy (Phase 0) AC Immune SA Tau Small Molecule
ASN51 ASN121151 Alzheimer's Disease (Inactive) Asceneuron SA Tau Small Molecule
Davunetide NAP,
AL-108
Mild Cognitive Impairment (Inactive), Progressive Supranuclear Palsy (Inactive), Schizophrenia (Inactive), Frontotemporal Dementia (Inactive), Autism Spectrum Disorder (Phase 3) Allon Therapeutics Inc., Exonavis Therapeutics Ltd., Paladin Labs Inc. Tau Other
Lithium lithium carbonate,
lithium aspartate,
lithium citrate,
lithium orotate
Alzheimer's Disease (Phase 4), Amyotrophic Lateral Sclerosis (Phase 3), Frontotemporal Dementia (Inactive), Mild Cognitive Impairment (Phase 4), Parkinson's Disease (Phase 2) Amyloid-Related, Tau, Metals, Other Other Bipolar disorder
PNT001 Alzheimer's Disease (Inactive), Traumatic Brain Injury (Inactive) Pinteon Therapeutics Tau Immunotherapy (passive)
Semorinemab RO7105705 ,
MTAU9937A,
RG6100
Alzheimer's Disease (Inactive) AC Immune SA, Genentech, Hoffmann-La Roche Tau Immunotherapy (passive)
TPI 287 Alzheimer's Disease (Inactive), Corticobasal Degeneration (Inactive), Progressive Supranuclear Palsy (Phase 1) Cortice Biosciences Tau Small Molecule