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Name Synonyms FDA Status Company Target Type Therapy Type Approved
For
Autologous Adipose-derived Stem Cells RB-ADSC,
CEREWiNT®,
Astrostem
Alzheimer's Disease (Phase 1/2) Regeneration Biomedical, Inc. Other Other
AVB-101 Frontotemporal Dementia (Phase 1/2) AviadoBio Other DNA/RNA-based
Bezisterim NE3107,
HE3286
Alzheimer's Disease (Phase 3), Parkinson's Disease (Phase 1/2) BioVie Pharma Inflammation, Other Small Molecule
CDNF cerebral dopamine neurotrophic factor Parkinson's Disease (Phase 1/2) Herantis Pharma Plc, Renishaw plc. Other Procedural Intervention, Other
Dapagliflozin Farxiga,
Forxiga,
BMS 512148
Alzheimer's Disease (Phase 1/2) AstraZeneca, Bristol-Myers Squibb Other Small Molecule
Dasatinib + Quercetin Alzheimer's Disease (Phase 1/2) Tau, Other Combination, Small Molecule, Supplement, Dietary
DNL593 PTV:PGRN,
TAK-594
Frontotemporal Dementia (Phase 1/2) Denali Therapeutics Inc., Takeda Pharmaceutical Company Other Other
Emrusolmin Anle138b,
TEV-56286
Parkinson's Disease (Phase 1/2), Multiple System Atrophy (Phase 2) MODAG GmbH, Teva Tau, alpha-synuclein, Other Small Molecule
LY3884961 PR001,
PR001A
Parkinson's Disease (Phase 1/2) Eli Lilly & Co., Prevail Therapeutics Other DNA/RNA-based
LY3884963 PR006 Frontotemporal Dementia (Phase 1/2) Eli Lilly & Co., Prevail Therapeutics Other DNA/RNA-based
Nicotinamide Riboside Niagen,
NR,
Nicotinamide,
Vitamin B3
Alzheimer's Disease (Phase 1), Parkinson's Disease (Phase 2), Mild Cognitive Impairment (Phase 1/2) ChromaDex, Others Other Supplement, Dietary
PBFT02 Frontotemporal Dementia (Phase 1/2) Passage Bio Other DNA/RNA-based