286387 RESULTS
SERIES Scientists are honing transferrin receptors to whisk bulky, anti-Aβ antibodies throughout the brain without setting off ARIA and anemia. By halving the effector function of their antibody transport vehicle, Denali researchers blunted red blood cell loss a
Laguna Beach, United States
COMMENT This study is of interest as it provides new insights into the sex dependence of the impact of ApoE4 on AD pathobiology. The inclusion of human data combined with experimental validation are major strengths of the paper. The identification of a new class
PAPER Venkatesh SS, Ganjgahi H, Palmer DS, Coley K, Linchangco GV Jr, Hui Q, Wilson P, Ho YL, Cho K, Arumäe K, Million Veteran Program, Estonian Biobank Research Team, Wittemans LB, Nellåker C, Vainik U, Sun YV, Holmes C, Lindgren CM, Nicholson G
IUUnited States
COMMENT These parallel discoveries by the Lee and Ryskeldi-Falcon teams are seminal. Together, they conclusively show that two distinct proteins, ANXA11 and TDP-43, co-assemble into organized heteromeric amyloid filaments in FTLD type C and in a subset of other T
COMMENT I think this is a very interesting and exciting discovery for several reasons. The finding of a novel type of filament as a consistent feature of FTLD-TDP type C samples confirms that these cases represent a distinct entity, and validates the current path
COMMENT In the beginning, amyloid was identified by tell-tale morphologic and staining characteristics, and little was known about its constituent proteins. As analytic methods progressed, amyloids became increasingly defined by their principal polymeric proteins
PAPER Nabizadeh F, Seyedmirzaei H, Karami S
PAPER Gallo A, Martone AM, Liperoti R, Cipriani MC, Ibba F, Camilli S, Rognoni FM, Landi F, Montalto M
PAPER Polsinelli AJ, Johnson S, Crouch A, Lane KA, Pena-Garcia A, Hammers DB, Wang S, Gao S, Apostolova LG
PAPER Luz S, Haider F, Fromm D, Lazarou I, Kompatsiaris I, Macwhinney B
PAPER Chinnathambi S, Desale SE
PAPER Owens CD, Pinto CB, Mukli P, Gulej R, Velez FS, Detwiler S, Olay L, Hoffmeister JR, Szarvas Z, Muranyi M, Peterfi A, Pinaffi-Langley AC, Adams C, Sharps J, Kaposzta Z, Prodan CI, Kirkpatrick AC, Tarantini S, Csiszar A, Ungvari Z, Olson AL, Li G, Balasubramanian P, Galvan V, Bauer A, Smith ZA, Dasari TW, Whitehead S, Medapti MR, Elahi FM, Thanou A, Yabluchanskiy A
PAPER Seok DH, Yang HW, Han JW, Lim JH, Kim SH, Kim EY, Kim KW
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