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An Idiosyncratic View of AD Biomarkers

WEBINAR 2006-06-15 Dr. Coleman led this live discussion on how biomarker information and basic science of AD can inform each other. He reviewed how the more common biomarkers of tau and Aß peptides relate to the major neurobiological deficits in AD—synaptic loss and dysfunc

Not Dead Yet: Estrogen Deserves Another Chance

WEBINAR 2006-01-28 You may think the Women’s Health Study has sounded the death knell for estrogen replacement therapy, but actually, the idea is showing new signs of life. A second-generation approach with better compounds may warrant continued investment, and yet, how doe

Reducing the Risk of Alzheimer Disease

WEBINAR 2005-12-23 The topic is an apt one to launch the new year: what factors in daily life can reduce one's risk of Alzheimer's disease? To fire up your neural networks, you are invited to read the recent review (download pdf) by Kathryn Jedrziewski, Virginia L

Are Glia Active Participants in Neurodegenerative Disease?

WEBINAR 2005-12-05 Ben Barres led the first in a series of Alzforum discussions about the role of glial cells in Alzheimer’s and other neurodegenerative diseases. It has become trendy to say that glia are more than just glue, but in reality, science has not yet advanced sig

100 Questions and Answers About Alzheimer's Disease

WEBINAR 2005-07-01 Are you a physician or caregiver thirsting for an update on the latest research on Alzheimer disease, or are you a basic researcher curious about the latest advances in clinical diagnosis and care?   Tom Wisniewski and Marcin Sadowski led this live discus

Differential Neuronal Vulnerability

WEBINAR 2005-06-29 Vikram Khurana and Ole Isacson led this live discussion on 29 June 2005. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Transcript: Live Discussion led by Ole Isacson and Vikram Khurana on 29 June 2

Now You See Them, Now You Don't: The Amyloid Channel Hypothesis

WEBINAR 2005-06-16 Ever since amyloid-β (Aβ) was identified as the major component in amyloid plaques, scientists have been trying to decipher just exactly what the little peptide does. Most researchers would agree that Aβ is toxic to cells, but some are still skeptical. Ev

Making a BioMark on Alzheimer Disease

WEBINAR 2005-06-01 Our thanks to Practical Neurology for granting permission to reprint the full text of a recent article (.pdf) by John Trojanowski. John Trojanowski, Les Shaw, and Anne Fagan led this live discussion on 1 June 2005. Readers are invited to submit additional

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BIOMOLECULE